miR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve Polycomb-mediated repression

Specification of the T helper 17 (Th17) cell lineage requires a well defined set of transcription factors, but how these integrate with post-transcriptional and epigenetic programs to regulate gene expression is poorly understood. Here we found defective Th17 cell cytokine expression in miR-155-defi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Escobar, Thelma M., Kanellopoulou, Chrysi, Kugler, David G., Kilaru, Gokhul, Nguyen, Cuong K., Nagarajan, Vijayaraj, Bhairavabhotla, Ravikiran K., Northrup, Daniel, Zahr, Rami, Burr, Patrick, Liu, Xiuhuai, Zhao, Keji, Sher, Alan, Jankovic, Dragana, Zhu, Jinfang, Muljo, Stefan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092165/
https://ncbi.nlm.nih.gov/pubmed/24856900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.03.014
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker