Ładuje się......
G-Protein Coupled Receptors Engage the Mammalian Hippo pathway through F-Actin: F-Actin, assembled in response to Galpha(12/13) induced RhoA-GTP, promotes dephosphorylation and activation of the YAP oncogene
The Hippo pathway, a cascade of protein kinases that inhibits the oncogenic transcriptional coactivators YAP and TAZ, was discovered in Drosophila as a major determinant of organ size in development. Known modes of regulation involve surface proteins that mediate cell-cell contact or determine epith...
Zapisane w:
| Główni autorzy: | , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2013
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4092039/ https://ncbi.nlm.nih.gov/pubmed/23450633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200163 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|