Φορτώνει......
Variability in Human Sensitivity to 1,3-Butadiene: Influence of Polymorphisms in the 5′-Flanking Region of the Microsomal Epoxide Hydrolase Gene (EPHX1)
The carcinogenic effects of 1,3-butadiene (BD), a mutagenic chemical widely used in the manufacture of synthetic rubber, are likely initiated through its epoxide metabolites. In humans, these epoxides are detoxified predominantly by hydrolysis, a reaction mediated by the microsomal epoxide hydrolase...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091891/ https://ncbi.nlm.nih.gov/pubmed/15716486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfi115 |
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