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Microsomal Epoxide Hydrolase 1 (EPHX1): Gene, Structure, Function, and Role in Human Disease

Microsomal epoxide hydrolase (EPHX1) is an evolutionarily highly conserved biotransformation enzyme for converting epoxides to diols. Notably, the enzyme is able to either detoxify or bioactivate a wide range of substrates. Mutations and polymorphic variants in the EPHX1 gene have been associated wi...

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Detalles Bibliográficos
Publicado en:Gene
Autores principales: Václavíková, Radka, Hughes, David J, Souček, Pavel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544754/
https://ncbi.nlm.nih.gov/pubmed/26216302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.07.071
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