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Microsomal Epoxide Hydrolase 1 (EPHX1): Gene, Structure, Function, and Role in Human Disease

Microsomal epoxide hydrolase (EPHX1) is an evolutionarily highly conserved biotransformation enzyme for converting epoxides to diols. Notably, the enzyme is able to either detoxify or bioactivate a wide range of substrates. Mutations and polymorphic variants in the EPHX1 gene have been associated wi...

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Detalhes bibliográficos
Publicado no:Gene
Main Authors: Václavíková, Radka, Hughes, David J, Souček, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544754/
https://ncbi.nlm.nih.gov/pubmed/26216302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.07.071
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