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Intronic DNA elements regulate Nrf-2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter

In humans, microsomal epoxide hydrolase (mEH) contributes important biological functions that underlie both detoxification and bioactivation fates arising from exposures to foreign chemicals. Previously, we discovered that human mEH gene transcription is initiated from alternative promoters. The res...

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Detalhes bibliográficos
Main Authors: Su, Shengzhong, Yang, Xi, Omiecinski, Curtis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040333/
https://ncbi.nlm.nih.gov/pubmed/24704207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.03.014
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