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Intronic DNA elements regulate Nrf-2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter

In humans, microsomal epoxide hydrolase (mEH) contributes important biological functions that underlie both detoxification and bioactivation fates arising from exposures to foreign chemicals. Previously, we discovered that human mEH gene transcription is initiated from alternative promoters. The res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Su, Shengzhong, Yang, Xi, Omiecinski, Curtis J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040333/
https://ncbi.nlm.nih.gov/pubmed/24704207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.03.014
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