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Hypoxia-targeted triple suicide gene therapy radiosensitizes human colorectal cancer cells
The hypoxic microenvironment, an important feature of human solid tumors but absent in normal tissue, may provide an opportunity for cancer-specific gene therapy. The purpose of the present study was to investigate whether hypoxia-driven triple suicide gene TK/CD/UPRT expression enhances cytotoxicit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091884/ https://ncbi.nlm.nih.gov/pubmed/24912473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.3238 |
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