Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo

PURPOSE: To investigate whether hypoxia targeted bifunctional suicide gene expression-cytosine deaminase (CD) and uracil phosphoribosyltransferase (UPRT) with 5-FC treatments can enhance radiotherapy. MATERIAL AND METHODS: Stable transfectant of R3327-AT cells were established which express a triple...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Sun, Xiaorong, Xing, Ligang, Deng, Xuelong, Hsiao, Hung Tsung, Manami, Akiko, Koutcher, Jason A., Ling, C. Clifton, Li, Gloria C.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747309/
https://ncbi.nlm.nih.gov/pubmed/22938726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2012.07.011
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares