Loading...

A triple suicide gene strategy that improves therapeutic effects and incorporates multi-modality molecular imaging for monitoring gene-functions

Gene-directed enzyme prodrug therapy (GDEPT), or suicide gene therapy, has shown promise in clinical trials. In this preclinical study using stable cell lines and xenograft tumor models, we show that a triple-suicide-gene GDEPT approach produce enhanced therapeutic efficacy over previous methods. Im...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Xing, Ligang, Sun, Xiaorong, Deng, Xuelong, Kotedia, Khushali, Zanzonico, Pat B., Ackerstaff, Ellen, Koutcher, Jason A., Ling, C. Clifton, Li, Gloria C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696018/
https://ncbi.nlm.nih.gov/pubmed/23722591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2013.28
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!