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IL-3/GM-CSF receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic Apoe deficiency
OBJECTIVE: Coronary heart disease is associated with monocytosis. Studies using animal models of monocytosis and atherosclerosis such as Apoe(-/-) mice have shown bone marrow (BM) hematopoietic stem and multi-potential progenitor cell (HSPC) expansion, associated with increased cell surface expressi...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091799/ https://ncbi.nlm.nih.gov/pubmed/24651678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.303097 |
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