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Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing
Next-generation sequencing has been used to infer the clonality of heterogeneous tumor samples. These analyses yield specific predictions—the population frequency of individual clones, their genetic composition, and their evolutionary relationships—which we set out to test by sequencing individual c...
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Glavni autori: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2014
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091781/ https://ncbi.nlm.nih.gov/pubmed/25010716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004462 |
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