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Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing

Next-generation sequencing has been used to infer the clonality of heterogeneous tumor samples. These analyses yield specific predictions—the population frequency of individual clones, their genetic composition, and their evolutionary relationships—which we set out to test by sequencing individual c...

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Bibliografski detalji
Glavni autori: Hughes, Andrew E. O., Magrini, Vincent, Demeter, Ryan, Miller, Christopher A., Fulton, Robert, Fulton, Lucinda L., Eades, William C., Elliott, Kevin, Heath, Sharon, Westervelt, Peter, Ding, Li, Conrad, Donald F., White, Brian S., Shao, Jin, Link, Daniel C., DiPersio, John F., Mardis, Elaine R., Wilson, Richard K., Ley, Timothy J., Walter, Matthew J., Graubert, Timothy A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091781/
https://ncbi.nlm.nih.gov/pubmed/25010716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004462
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