An Investigational Antiviral Drug, DAS181, Effectively Inhibits Replication of Zoonotic Influenza A Virus Subtype H7N9 and Protects Mice From Lethality

Human infections caused by avian influenza A virus type subtype H7N9 have been associated with substantial morbidity and mortality. Emergence of virus variants carrying markers of decreased susceptibility to neuraminidase inhibitors was reported. Here we show that DAS181 (Fludase), an antiviral drug...

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Bibliografske podrobnosti
Main Authors: Marjuki, Henju, Mishin, Vasiliy P., Chesnokov, Anton P., De La Cruz, Juan A., Fry, Alicia M., Villanueva, Julie, Gubareva, Larisa V.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Major Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091581/
https://ncbi.nlm.nih.gov/pubmed/24569063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu105
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