An Investigational Antiviral Drug, DAS181, Effectively Inhibits Replication of Zoonotic Influenza A Virus Subtype H7N9 and Protects Mice From Lethality

Human infections caused by avian influenza A virus type subtype H7N9 have been associated with substantial morbidity and mortality. Emergence of virus variants carrying markers of decreased susceptibility to neuraminidase inhibitors was reported. Here we show that DAS181 (Fludase), an antiviral drug...

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Bibliographic Details
Main Authors: Marjuki, Henju, Mishin, Vasiliy P., Chesnokov, Anton P., De La Cruz, Juan A., Fry, Alicia M., Villanueva, Julie, Gubareva, Larisa V.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091581/
https://ncbi.nlm.nih.gov/pubmed/24569063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu105
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