Загрузка...

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

BACKGROUND: Atopic dermatitis (AD; eczema) is characterized by a widespread abnormality in cutaneous barrier function and propensity to inflammation. Filaggrin is a multifunctional protein and plays a key role in skin barrier formation. Loss-of-function mutations in the gene encoding filaggrin (FLG)...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Cole, Christian, Kroboth, Karin, Schurch, Nicholas J., Sandilands, Aileen, Sherstnev, Alexander, O'Regan, Grainne M., Watson, Rosemarie M., Irwin McLean, W.H., Barton, Geoffrey J., Irvine, Alan D., Brown, Sara J.
Формат: Artigo
Язык:Inglês
Опубликовано: Mosby 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090750/
https://ncbi.nlm.nih.gov/pubmed/24880632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.04.021
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!