TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen

TLR5-deficient mice have been reported to develop spontaneous intestinal inflammation and metabolic abnormalities. However, we report that TLR5-deficient mice from two different animal colonies display no evidence of basal inflammatory disease, metabolic abnormalities, or enhanced resistance to Salm...

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Detalhes bibliográficos
Main Authors: Letran, Shirdi E., Lee, Seung-Joo, Atif, Shaikh M., Flores-Langarica, Adriana, Uematsu, Satoshi, Akira, Shizuo, Cunningham, Adam F., McSorley, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090138/
https://ncbi.nlm.nih.gov/pubmed/21451112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003576
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