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Bio-layer Interferometry for Measuring Kinetics of Protein-protein Interactions and Allosteric Ligand Effects

We describe the use of Bio-layer Interferometry to study inhibitory interactions of subunit ε with the catalytic complex of Escherichia coli ATP synthase. Bacterial F-type ATP synthaseis the target of a new, FDA-approved antibiotic to combat drug-resistant tuberculosis. Understanding bacteria-specif...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shah, Naman B., Duncan, Thomas M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MyJove Corporation 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089413/
https://ncbi.nlm.nih.gov/pubmed/24638157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51383
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