Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells

AIM: To investigate whether Src, JAK2 and phosphatidylinositol 3-kinase (PI3K) pathways are involved in the proliferation of human colonic tumour cells induced by glycine-extended gastrin (G-gly), the precursor of the mature amidated gastrin and to elucidate the molecular interaction between these t...

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Autores principales: Ferrand, Audrey, Kowalski-Chauvel, Aline, Pannequin, Julie, Bertrand, Claudine, Fourmy, Daniel, Dufresne, Marlene, Seva, Catherine
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2006
Materias:
Colorectal Cancer
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087510/
https://ncbi.nlm.nih.gov/pubmed/16609991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i12.1859
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