Repurposing the FDA-Approved Pinworm Drug Pyrvinium as a Novel Chemotherapeutic Agent for Intestinal Polyposis

Mutations in the WNT-pathway regulator ADENOMATOUS POLYPOSIS COLI (APC) promote aberrant activation of the WNT pathway that is responsible for APC-associated diseases such as Familial Adenomatous Polyposis (FAP) and 85% of spontaneous colorectal cancers (CRC). FAP is characterized by multiple intest...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Li, Bin, Flaveny, Colin A., Giambelli, Camilla, Fei, Dennis Liang, Han, Lu, Hang, Brian I., Bai, Feng, Pei, Xin-Hai, Nose, Vania, Burlingame, Oname, Capobianco, Anthony J., Orton, Darren, Lee, Ethan, Robbins, David J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086981/
https://ncbi.nlm.nih.gov/pubmed/25003333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101969
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍