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Necessary, but not Sufficient: Insights into the Mechanisms of mGluR Mediated Long Term Depression from a Rat Model of Early Life Seizures
Using the rat model of early life seizures (ELS), which has exaggerated mGluR mediated long-term depression of synaptic strength (mGluR-LTD) in adulthood, we probed the signaling cascades underlying mGluR-LTD induction. Several inhibitors completely blocked mGluR-LTD in control but not in ELS rats:...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086946/ https://ncbi.nlm.nih.gov/pubmed/24780380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.04.011 |
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