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Presynaptic m1 muscarinic receptors are necessary for mGluR long-term depression in the hippocampus

To investigate the role of M1 muscarininc acetylcholine receptors (m1 receptors) in metabotropic glutamate receptor (mGluR)-mediated long-term depression (LTD), we produced mouse lines in which deletion of the m1 gene is restricted to the forebrain (FB–m1KO) or hippocampal CA3 pyramidal neurons (CA3...

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Autori principali: Kamsler, Ariel, McHugh, Thomas J., Gerber, David, Huang, Shu Ying, Tonegawa, Susumu
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824405/
https://ncbi.nlm.nih.gov/pubmed/20080609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912540107
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