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Group 1 mGluR-dependent synaptic long-term depression (mGluR-LTD): mechanisms and implications for circuitry & disease

Many excitatory synapses express Group 1, or Gq coupled, metabotropic glutamate receptors (Gp1 mGluRs) at the periphery of their postsynaptic density. Activation of Gp1 mGluRs typically occurs in response to strong activity and triggers long-term plasticity of synaptic transmission in many brain reg...

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Bibliografiske detaljer
Main Authors: Lüscher, Christian, Huber, Kimberly M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841961/
https://ncbi.nlm.nih.gov/pubmed/20188650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.01.016
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