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mGluR5 Facilitates Long-Term Synaptic Depression in a Stress-Induced Depressive Mouse Model

BACKGROUND: Glutamatergic system has been known to play a role in the pathogenesis of major depression disorder by inducing N-methyl-d-aspartate receptor-dependent long-term depression (LTD) or metabotropic glutamate receptors (mGluR)-dependent LTD. Here, we characterized the LTD in a chronic social...

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Detalhes bibliográficos
Publicado no:Can J Psychiatry
Main Authors: Jiang, Xiangzhi, Lin, Wei, Cheng, Yuanyuan, Wang, Dongming
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265615/
https://ncbi.nlm.nih.gov/pubmed/31526043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0706743719874162
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