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Group I mGluR Induced LTD of NMDAR-synaptic Transmission at the Schaffer Collateral but not Temperoammonic Input to CA1

NMDA receptors are composed of multiple subunits and are crucial in the induction of synaptic plasticity and learning and memory. In this study, application of the group I mGlu receptor agonist, DHPG, caused LTD of NMDA-EPSCs (DHPG-LTD(NMDA)) of the Schaffer collateral, but not of NMDA-EPSCs of the...

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Detalhes bibliográficos
Publicado no:Curr Neuropharmacol
Main Authors: Fitzjohn, Stephen, Bashir, Zafar, Farrow, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983758/
https://ncbi.nlm.nih.gov/pubmed/27296639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X13666150615221502
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