CYP3A4 overexpression enhances the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in CHO cells

AIM: To examine how the higher expression level of CYP3A4 isoenzyme influenced the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in Chinese hamster ovary (CHO) cells. METHODS: Three CHO cell lines were examined: wild-type CHO cells; CHO-HR cells with overexpression of human cyto...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Augustin, Ewa, Borowa-Mazgaj, Barbara, Kikulska, Agnieszka, Kordalewska, Milena, Pawłowska, Monika
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086498/
https://ncbi.nlm.nih.gov/pubmed/23160340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.132
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky