Enhanced Activity of P4503A4 and UGT1A10 Induced by Acridinone Derivatives C-1305 and C-1311 in MCF-7 and HCT116 Cancer Cells: Consequences for the Drugs’ Cytotoxicity, Metabolism and Cellular Response

Lignende værker

• Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
  af: Pawlowska, Monika, et al.
  Udgivet: (2013)
• CYP3A4 overexpression enhances apoptosis induced by anticancer agent imidazoacridinone C-1311, but does not change the metabolism of C-1311 in CHO cells
  af: Pawłowska, Monika, et al.
  Udgivet: (2014)
• Role of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10
  af: Fedejko-Kap, Barbara, et al.
  Udgivet: (2012)
• Electrochemical and in silico approaches for liver metabolic oxidation of antitumor-active triazoloacridinone C-1305()
  af: Potęga, Agnieszka, et al.
  Udgivet: (2020)
• CYP3A4 overexpression enhances the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in CHO cells
  af: Augustin, Ewa, et al.
  Udgivet: (2013)