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Chemoselective attachment of small molecule effector functionality to human adenoviruses facilitates gene delivery to cancer cells
Azide-enabled adenovirus for gene delivery: We demonstrate here a novel two-step “click” labeling process in which adenoviral particles are first metabolically labeled during production with unnatural azido sugars. Subsequent chemoselective modification allows access to viruses decorated with a broa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086407/ https://ncbi.nlm.nih.gov/pubmed/20831164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104547x |
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