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Targeted and armed oncolytic adenovirus via chemoselective modification

Oncolytic adenoviruses (Ads) are an emerging alternative therapy for cancer; however, clinical trial have not yet demonstrated sufficient efficacy. When oncolytic Ads are used in combination with taxoids a synergistic increase in both cytotoxicity and viral replication is observed. In order to gener...

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Detalles Bibliográficos
Main Authors: Banerjee, Partha S., Zuniga, Edison S., Ojima, Iwao, Carrico, Isaac S.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413283/
https://ncbi.nlm.nih.gov/pubmed/21669527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.05.039
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