Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells

Loss of p53 gene function, which occurs in most colon cancer cells, has been shown to abolish the apoptotic response to 5-fluorouracil (5-FU). To identify genes downstream of p53 that might mediate these effects, we assessed global patterns of gene expression following 5-FU treatment of isogenic cel...

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Détails bibliographiques
Auteurs principaux: Hwang, Paul M., Bunz, Fred, Yu, Jian, Rago, Carlo, Chan, Timothy A., Murphy, Michael P., Kelso, Geoffry F., Smith, Robin A. J., Kinzler, Kenneth W., Vogelstein, Bert
Format: Artigo
Langue:Inglês
Publié: 2001
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086305/
https://ncbi.nlm.nih.gov/pubmed/11590433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1001-1111
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