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Influence of 5-fluorouracil on ferredoxin reductase mRNA splice variants in colorectal carcinomas

5-Fluorouracil (5-FU) is a frequently used antitumor drug. Recently, it has been shown that mRNA and protein levels of the ferredoxin reductase gene (gene, FDXR; protein, FR) increase drastically after 5-FU treatment in various cell lines including colorectal cancer. The induction is mediated by p53...

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Dettagli Bibliografici
Autori principali: SCHNEIDER, MARK, TANAKA-NOZAKI, MOTOKO, KATO, SHUNJI, BLÖMEKE, BRUNHILDE
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436463/
https://ncbi.nlm.nih.gov/pubmed/22966307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol_00000062
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