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Activation of the Stimulator of Interferon Genes (STING) adaptor attenuates experimental autoimmune encephalitis
Cytosolic DNA sensing activates the Stimulator of Interferon Genes (STING) adaptor to induce interferon type I (IFNαβ) production. Constitutive DNA sensing to induce sustained STING activation incites tolerance breakdown leading to autoimmunity. Here we show that systemic treatments with DNA nanopar...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086255/ https://ncbi.nlm.nih.gov/pubmed/24799564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303258 |
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