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STING promotes the growth of tumors characterized by low antigenicity via IDO activation

Cytosolic DNA sensing is an important process during the innate immune response that activates the Stimulator of Interferon Genes (STING) adaptor and induce interferon type I (IFN-I). STING incites spontaneous immunity during immunogenic tumor growth and accordingly, STING agonists induce regression...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Lemos, Henrique, Mohamed, Eslam, Huang, Lei, Ou, Rong, Pacholczyk, Gabriela, Arbab, Ali S., Munn, David, Mellor, Andrew L
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873329/
https://ncbi.nlm.nih.gov/pubmed/26964621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1456
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