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ARRY-334543 reverses multidrug resistance by antagonizing the activity of ATP-binding cassette subfamily G member 2
BACKGROUND: ARRY-334543 is a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases. We conducted this study to determine whether ARRY-334543 can enhance the efficacy of conventional anticancer drugs through interaction with ABC transporters. METHODS: Lung cancer cell line NCI-H460 and its ABC...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4086246/ https://ncbi.nlm.nih.gov/pubmed/24939447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24787 |
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