N-acetylcysteineamide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI

Traumatic brain injury (TBI) has become a growing epidemic but no approved pharmacological treatment has been identified. Our previous work indicates that mitochondrial oxidative stress/damage and loss of bioenergetics play a pivotal role in neuronal cell death and behavioral outcome following exper...

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Main Authors: Pandya, Jignesh D., Readnower, Ryan D., Patel, Samir P., Yonutas, Heather M., Pauly, James R., Goldstein, Glenn A., Rabchevsky, Alexander G., Sullivan, Patrick G.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086163/
https://ncbi.nlm.nih.gov/pubmed/24792639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.04.020
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