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Muscle matters in Kennedy’s disease

Polyglutamine expansion in the androgen receptor causes Kennedy’s disease. Two recent reports raise the possibility that targeting expression of the mutant protein in skeletal muscle, instead of the nervous system, may mitigate manifestations of this disorder.

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Autors principals: Rinaldi, Carlo, Bott, Laura C., Fischbeck, Kenneth H.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086161/
https://ncbi.nlm.nih.gov/pubmed/24742452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.04.005
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