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Androgen receptor mutation in Kennedy's disease.

Kennedy's disease is an X-linked form of motor neuron disease caused by an expanded polyglutamine repeat in the androgen receptor. While the expansion mutation causes some loss of transcriptional activity by the androgen receptor, the predominant effect of expansion is probably a toxic gain of...

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Detalles Bibliográficos
Main Authors: Fischbeck, K H, Lieberman, A, Bailey, C K, Abel, A, Merry, D E
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1692603/
https://ncbi.nlm.nih.gov/pubmed/10434308
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