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Copy number variants are produced in response to low-dose ionizing radiation in cultured cells

Despite their importance to human genetic variation and disease, little is known about the molecular mechanisms and environmental risk factors that impact copy number variant (CNV) formation. While it is clear that replication stress can lead to de novo CNVs, for example following treatment of cultu...

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Bibliographische Detailangaben
Hauptverfasser: Arlt, Martin F., Rajendran, Sountharia, Birkeland, Shanda R., Wilson, Thomas E., Glover, Thomas W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086151/
https://ncbi.nlm.nih.gov/pubmed/24327335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21840
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