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Accurate phosphoregulation of kinetochore–microtubule affinity requires unconstrained molecular interactions
Accurate chromosome segregation relies on dynamic interactions between microtubules (MTs) and the NDC80 complex, a major kinetochore MT-binding component. Phosphorylation at multiple residues of its Hec1 subunit may tune kinetochore–MT binding affinity for diverse mitotic functions, but molecular de...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085703/ https://ncbi.nlm.nih.gov/pubmed/24982430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201312107 |
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