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The binding of Borealin to microtubules underlies a tension independent kinetochore-microtubule error correction pathway

Proper chromosome segregation depends upon kinetochore phosphorylation by the Chromosome Passenger Complex (CPC). Current models suggest the activity of the CPC decreases in response to the inter-kinetochore stretch that accompanies the formation of bi-oriented microtubule attachments, however littl...

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Vydáno v:Nat Commun
Hlavní autoři: Trivedi, Prasad, Zaytsev, Anatoly V., Godzi, Maxim, Ataullakhanov, Fazly I., Grishchuk, Ekaterina L., Stukenberg, P. Todd
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368601/
https://ncbi.nlm.nih.gov/pubmed/30737408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08418-4
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