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Basic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules

Accuracy of chromosome segregation relies on the ill-understood ability of mitotic kinetochores to biorient, whereupon each sister kinetochore forms microtubule (MT) attachments to only one spindle pole. Because initial MT attachments result from chance encounters with the kinetochores, biorientatio...

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Foilsithe in:Mol Biol Cell
Main Authors: Zaytsev, Anatoly V., Grishchuk, Ekaterina L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710231/
https://ncbi.nlm.nih.gov/pubmed/26424798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0384
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