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Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity
Microtubule (MT) attachment to kinetochores is vitally important for cell division, but how these interactions are controlled by phosphorylation is not well known. We used quantitative approaches in vitro combined with molecular dynamics simulations to examine phosphoregulation of the NDC80 complex,...
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| Pubblicato in: | Mol Biol Cell |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4436829/ https://ncbi.nlm.nih.gov/pubmed/25808492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-11-1539 |
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