Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy

Multiple mutations in cardiac troponin T (cTnT) can cause familial hypertrophic cardiomyopathy (FHC). Patients with cTnT mutations generally exhibit mild or no ventricular hypertrophy, yet demonstrate a high frequency of early sudden death. To understand the functional basis of these phenotypes, we...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Tardiff, Jil C., Hewett, Timothy E., Palmer, Bradley M., Olsson, Charlotte, Factor, Stephen M., Moore, Russell L., Robbins, Jeffrey, Leinwand, Leslie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1999
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI6067
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky