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Detecting Signals in Pharmacogenomic Genome-Wide Association Studies
In one common pharmacogenomic scenario, outcome measures are compared for treated and untreated subjects across genotype defined subgroups. The key question is whether treatment benefit (or harm) is particularly strong in certain subgroups, and therefore statistical analysis focuses on the interacti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4085158/ https://ncbi.nlm.nih.gov/pubmed/24394200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2013.44 |
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