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A Conceptual Framework for Pharmacodynamic Genome-wide Association Studies in Pharmacogenomics
Genome-wide association studies (GWAS) have emerged as a powerful tool to identify loci that affect drug response or susceptibility to adverse drug reactions. However, current GWAS based on a simple analysis of associations between genotype and phenotype ignores the biochemical reactions of drug res...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4029408/ https://ncbi.nlm.nih.gov/pubmed/21920452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2011.09.001 |
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