Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma

BACKGROUND: Genome-wide association study (GWAS) is a powerful tool to identify novel pharmacogenetic single nucleotide polymorphisms (SNPs). Leukotriene receptor antagonists (LTRAs) are a major class of asthma medications, and genetic factors contribute to variable responses to these drugs. We used...

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Pubblicato in:PLoS One
Autori principali: Dahlin, Amber, Litonjua, Augusto, Lima, John J., Tamari, Mayumi, Kubo, Michiaki, Irvin, Charles G., Peters, Stephen P., Tantisira, Kelan G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470685/
https://ncbi.nlm.nih.gov/pubmed/26083242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129385
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