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Detecting Signals in Pharmacogenomic Genome-Wide Association Studies

In one common pharmacogenomic scenario, outcome measures are compared for treated and untreated subjects across genotype defined subgroups. The key question is whether treatment benefit (or harm) is particularly strong in certain subgroups, and therefore statistical analysis focuses on the interacti...

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Bibliografske podrobnosti
Main Authors: Wakefield, Jon, Skrivankova, Veronika, Hsu, Fang-Chi, Sale, Michele, Heagerty, Patrick
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085158/
https://ncbi.nlm.nih.gov/pubmed/24394200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2013.44
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