The Targeted Transduction of MMP-Overexpressing Tumor Cells by ACPP-HPMA Copolymer-Coated Adenovirus Conjugates

We have designed and tested a new way to selectively deliver HPMA polymer-coated adenovirus type 5 (Ad5) particles into matrix metalloproteinase (MMP)-overexpressing tumor cells. An activatable cell penetrating peptide (ACPP) was designed and attached to the reactive 4-nitrophenoxy groups of HPMA po...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Li, Shuhua, Chen, Juanzhi, Xu, Huiyong, Long, Jie, Xie, Xiaobin, Zhang, Yajie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085062/
https://ncbi.nlm.nih.gov/pubmed/25000246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100670
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados