Traceless Bioresponsive Shielding of Adenovirus Hexon with HPMA Copolymers Maintains Transduction Capacity In Vitro and In Vivo

Capsid surface shielding of adenovirus vectors with synthetic polymers is an emerging technology to reduce unwanted interactions of the vector particles with cellular and non-cellular host components. While it has been shown that attachment of shielding polymers allows prevention of undesired intera...

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Detalhes bibliográficos
Main Authors: Prill, Jan-Michael, Šubr, Vladimír, Pasquarelli, Noemi, Engler, Tatjana, Hoffmeister, Andrea, Kochanek, Stefan, Ulbrich, Karel, Kreppel, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903484/
https://ncbi.nlm.nih.gov/pubmed/24475024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082716
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