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The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

Recent data point to the contribution of P-glycoprotein (P-gp) to digoxin elimination. On the basis of clinical observations of patients in whom digoxin levels decreased considerably when treated with rifampin, we hypothesized that concomitant rifampin therapy may affect digoxin disposition in human...

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Main Authors: Greiner, Bernd, Eichelbaum, Michel, Fritz, Peter, Kreichgauer, Hans-Peter, von Richter, Oliver, Zundler, Johannes, Kroemer, Heyo K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 1999
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC408477/
https://ncbi.nlm.nih.gov/pubmed/10411543
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