CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

Engagement of the B7 family of molecules on antigen-presenting cells with their T cell–associated ligands, CD28 and CD152 (cytotoxic T lymphocyte–associated antigen-4 [CTLA-4]), provides a pivotal costimulatory signal in T-cell activation. We investigated the role of the CD28/CD152 pathway in psoria...

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Main Authors: Abrams, Judith R., Lebwohl, Mark G., Guzzo, Cynthia A., Jegasothy, Brian V., Goldfarb, Michael T., Goffe, Bernard S., Menter, Alan, Lowe, Nicholas J., Krueger, Gerald, Brown, Michael J., Weiner, Russell S., Birkhofer, Martin J., Warner, Garvin L., Berry, Karen K., Linsley, Peter S., Krueger, James G., Ochs, Hans D., Kelley, Susan L., Kang, Sewon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408469/
https://ncbi.nlm.nih.gov/pubmed/10225967
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